Noreva IKLEN Depigmenting Cream
Prevents the Appearance of Brown Spots

♦ Regulates and prevents brown marks caused by abnormal pigmentation.
♦ Rucinol inhibits melanin production and spots from developing.
♦ Moisturizing, fragrance-free formula is easily applied, tolerated and absorbed by skin.

30 ml tube

Apply morning and evening to the hyperpigmented areas, before applying usual skin care (day or night cream, make-up). There is no need to limit the application to the darker areas only: Iklen can be safely applied to larger areas. Apply softly, without rubbing (friction enhances the overproduction of melanin). You can expect to see visible results after 4 weeks and continued improvement over the following months. It is recommended that you use Iklen Serum and/or Cream for 8 - 12 weeks. Add a high sun protection during sun exposure (minimum SPF 30).

Rucinol�

Rucinol� (a patented ingredient) works on the biochemical pathway by which melanin (colour in the skin) is produced.

Rucinol� inhibits an enzyme called tyrosinase, thereby reducing the production of the darker melanins.

• Rucinol� also inhibits another enzyme called TRP1
• The inhibition of TRP1 will shift production of black melanin towards brown or pale melanins (phaeomelanin).
• Overview of the mode of action:
• By acting in two places (on tyrosinase and TRP1), Rucinol� reduces and lightens the melanosomes. It is therefore an effective depigmenting agent.

Sophora-alpha

• Sophora-alpha acts on the outside of the melanocyte, and blocks the extracellular action of alpha-MSH, by blocking MSH receptors.
• Alpha-MSH is responsible for activating the melanin synthesis pathway.